Testosterone Profile



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Buy Testosterone Profile Online. As a bodybuilding drug, testosterone is almost always used as an injectable ester, because of poor oral bioavailability and the impracticality of high-dose transdermal or sublingual delivery. We also provide testosterone as an injectable suspension. The discussion here is in reference to these injectable preparations.

Pharmacologically, testosterone acts both via the androgen receptor and via other means. It is found to combine synergistically both with those anabolic steroids categorized as Class we, therefore, describe me and those categorized as Class II and as having mixed activity. Buy testing 400.

Particular properties of testosterone that are of note include that it converts enzymatically both to dihydrotestosterone (DHT) and to estradiol (the most important of the estrogens.)

While with normal levels of testosterone and normal enzyme activity, these conversions are in fact desirable, with supraphysiological testosterone levels caused by drug administration they can be undesirable.

DHT is at least three times more potent (effective per milligram) than testosterone at the androgen receptor (AR): therefore, in those tissues which convert testosterone to DHT, there is effectively three times as much androgen as elsewhere in the body.

Thus, whatever level of androgen is experienced by the muscle tissue is effectively multiplied threefold or more in the skin and in the prostate. This can be excessive. Buy Testonon 400.

Dutasteride (Avodart) can keep DHT levels normalized despite heavy testosterone use. Most users do not do this out of concern for excessively reducing DHT, which may be a valid concern at full-label dosing, but which I do not think is a concern with low-dose use (½ tab every other day) in a high-dose testosterone cycle.

Finasteride (Proscar) may be employed instead if one wishes to use a 5-alpha-reductase inhibitor. Here, in a high-dose testosterone cycle, one tab (5 mg) of this drug per day is unlikely to excessively decrease DHT.

Excess conversion to estrogen is another undesirable occurrence since it contributes to inhibition of the hypothalamic/pituitary/testicular axis (HPTA), can cause or aggravate gynecomastia, can cause bloating, and can give unfavorable fat pattern distribution. Buy Testonon 400.

This conversion can be controlled by the use of aromatase inhibitors such as Arimidex or letrozole, and/or the effects of excess estradiol may be blocked in relevant tissues by Clomid or Nolvadex.

Among the most significant differences between synthetic anabolic steroids compared to testosterone is that they may avoid either or both of these enzymatic conversions. In the past, this was a very important advantage. However, now that these conversions can be well-controlled, high-dose testosterone need not have all the adverse side effects that once inevitably accompanied its use.

Testosterone used as the sole androgen can give very effective results, particularly with doses of one gram or more per week, and can give substantial results with only 500 mg/week. If no other drugs are used to control estrogen, however, side effects such as gynecomastia are fairly likely.

Prostate enlargement, acne or worsening of acne, and acceleration of male pattern baldness (for those genetically susceptible to it) are more problematic with testosterone–again, in the absence of enzymatic control than with many synthetics because of the effectively higher androgen levels seen in these tissues because of local conversion to the more-potent DHT.

So, to minimize these effects, the choices for a highly effective cycle that is low in side effects are to either control these enzymatic conversions with ancillary compounds while using testosterone at high doses; to instead use synthetics that do not undergo these conversions, or to combine moderate dose testosterone (100-200 mg/week) with synthetics. Buy Testonon 400.

An anti-aromatase is preferable in a testosterone cycle to a selective estrogen receptor modulator (SERM) such as Clomid or Nolvadex for controlling estrogen because the SERMs either do nothing towards reducing the effect of elevated estrogen in aggravating or causing acne, or themselves contribute adversely. Abnormally elevated estrogen levels may be deleterious for other reasons.

Regarding inhibition of the hypothalamic/pituitary/testicular axis (HPTA), 200 mg/week of injected testosterone is approximately 2/3 to 3./4 suppressive, while 100 mg/week is about 50% suppressive.

For this reason, low-dose testosterone use is not efficient, as natural production is already “worth” 100-200 mg/week, and this is mostly lost with the first 200 mg/week of injectable that is used.

The particular synthetics which are low-suppressive are, for this reason, more efficient for low-dose use than testosterone. Buy Testonon 400

To plan HPTA recovery after a cycle, for the above reason, there is little point in beginning post-cycle therapy (PCT) until testosterone levels from the cycle have fallen to be commensurate with the use of only about 200 mg/week.

So, for example, if using 800 mg/week, it would be advisable to wait for two half-lives. (After several days equal to the half-life, levels will drop to that commensurate with 400 mg/week use, and after that same number of days again levels will again fall in half, now to levels commensurate with 200 mg/week use.)

So, for example, if the half-life of the ester used were 5 days, one would wait 10 days after the last injection to begin PCT, when the drug in question is testosterone, because of the details of its suppressive properties. Buy testing 400.

With the use of an anti-aromatase, 600-750 mg/week of injected testosterone is a good dosage range for a novice.

Without an anti-aromatase, it may be preferred to limit usage to 500 mg/week, although there can be a risk of gynecomastia at doses even as low as 200 mg/week if no anti-estrogen is used. More advanced users may favor one gram of testosterone per week.

Still-higher doses such as 2 grams per week provide only a small further increment in performance, with that being noticeable only if a plateau has been reached at 1 gram per week.

Some pro bodybuilders but probably with only a slight further incremental effect employ amounts higher than this. Buy Testonon 400


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